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Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells

Giardia intestinalis is a microaerophilic protozoan that is an important etiologic agent of diarrhea worldwide. There is evidence that under diverse conditions, the parasite is capable of shedding extracellular vesicles (EVs) which modulate the physiopathology of giardiasis. Here we describe new fea...

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Detalles Bibliográficos
Autores principales: Gavinho, Bruno, Sabatke, Bruna, Feijoli, Veronica, Rossi, Izadora Volpato, da Silva, Janaina Macedo, Evans-Osses, Ingrid, Palmisano, Giuseppe, Lange, Sigrun, Ramirez, Marcel Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539837/
https://www.ncbi.nlm.nih.gov/pubmed/33072615
http://dx.doi.org/10.3389/fcimb.2020.00417