SP1‐mediated upregulation of LINGO‐1 promotes degeneration of retinal ganglion cells in optic nerve injury

BACKGROUNDS: Insults to the axons in the optic nerve head are the primary cause of loss of retinal ganglion cells (RGCs) in traumatic, ischemic nerve injury or degenerative ocular diseases. The central nervous system–specific leucine‐rich repeat protein, LINGO‐1, negatively regulates axon regenerati...

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Detalles Bibliográficos
Autores principales: Wu, Yali, Zhan, Zongyi, Quan, Yadan, Yang, Yangfan, Chen, Xiaotao, Liu, Liling, Wu, Kaili, Yu, Minbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539844/
https://www.ncbi.nlm.nih.gov/pubmed/32562344
http://dx.doi.org/10.1111/cns.13426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539844/
https://www.ncbi.nlm.nih.gov/pubmed/32562344
http://dx.doi.org/10.1111/cns.13426

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