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SP1‐mediated upregulation of LINGO‐1 promotes degeneration of retinal ganglion cells in optic nerve injury
BACKGROUNDS: Insults to the axons in the optic nerve head are the primary cause of loss of retinal ganglion cells (RGCs) in traumatic, ischemic nerve injury or degenerative ocular diseases. The central nervous system–specific leucine‐rich repeat protein, LINGO‐1, negatively regulates axon regenerati...
Autores principales: | Wu, Yali, Zhan, Zongyi, Quan, Yadan, Yang, Yangfan, Chen, Xiaotao, Liu, Liling, Wu, Kaili, Yu, Minbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539844/ https://www.ncbi.nlm.nih.gov/pubmed/32562344 http://dx.doi.org/10.1111/cns.13426 |
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