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The measurement of KRAS G12 mutants using multiplexed selected reaction monitoring and ion mobility mass spectrometry

RATIONALE: There is a considerable clinical demand to determine key mutations in genes involved with cancer which necessitates the deployment of highly specific and robust analytical methods. Multiplex liquid chromatography with selected reaction monitoring (LC/SRM) assays offer the ability to achie...

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Detalles Bibliográficos
Autores principales: Norman, Rachel L, Singh, Rajinder, Langridge, James I., Ng, Leong L., Jones, Donald J.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539944/
https://www.ncbi.nlm.nih.gov/pubmed/31800120
http://dx.doi.org/10.1002/rcm.8657