Systematic Optimization of the iMALDI Workflow for the Robust and Straightforward Quantification of Signaling Proteins in Cancer Cells

PURPOSE: Immuno‐MALDI (iMALDI) combines immuno‐enrichment of biomarkers with MALDI‐MS for fast, precise, and specific quantitation, making it a valuable tool for developing clinical assays. iMALDI assays are optimized for the PI3‐kinase signaling pathway members phosphatase and tensin homolog (PTEN)...

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Detalles Bibliográficos
Autores principales: Froehlich, Bjoern C., Popp, Robert, Sobsey, Constance A., Ibrahim, Sahar, LeBlanc, Andre M., Mohammed, Yassene, Aguilar‐Mahecha, Adriana, Poetz, Oliver, Chen, Michael X., Spatz, Alan, Basik, Mark, Batist, Gerald, Zahedi, René P., Borchers, Christoph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539945/
https://www.ncbi.nlm.nih.gov/pubmed/32643306
http://dx.doi.org/10.1002/prca.202000034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539945/
https://www.ncbi.nlm.nih.gov/pubmed/32643306
http://dx.doi.org/10.1002/prca.202000034

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