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Hypoxia‐inducible factor 2α drives hepatosteatosis through the fatty acid translocase CD36

BACKGROUND & AIMS: Molecular mechanisms by which hypoxia might contribute to hepatosteatosis, the earliest stage in non‐alcoholic fatty liver disease (NAFLD) pathogenesis, remain still to be elucidated. We aimed to assess the impact of hypoxia‐inducible factor 2α (HIF2α) on the fatty acid transl...

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Detalles Bibliográficos
Autores principales: Rey, Esther, Meléndez‐Rodríguez, Florinda, Marañón, Patricia, Gil‐Valle, Miriam, Carrasco, Almudena G., Torres‐Capelli, Mar, Chávez, Stephania, del Pozo‐Maroto, Elvira, Rodríguez de Cía, Javier, Aragonés, Julián, García‐Monzón, Carmelo, González‐Rodríguez, Águeda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539965/
https://www.ncbi.nlm.nih.gov/pubmed/32432822
http://dx.doi.org/10.1111/liv.14519