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A Multitarget Gold(I) Complex Induces Cytotoxicity Related to Aneuploidy in HCT‐116 Colorectal Carcinoma Cells

A novel alkynyl phosphane gold(I) complex (trimethylphosphane)(3‐(1,3‐dimethylxanthine‐7‐yl)prop‐1‐yn‐1‐yl)gold(I) 1 displayed mutiple biological activites including selective proliferation inhibitory, anti‐metastatic, and anti‐angiogenic effects. The complex also induced effects related to aneuploi...

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Detalles Bibliográficos
Autores principales: Zhang, Jing‐Jing, Abu el Maaty, Mohamed A., Hoffmeister, Henrik, Schmidt, Claudia, Muenzner, Julienne K., Schobert, Rainer, Wölfl, Stefan, Ott, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540060/
https://www.ncbi.nlm.nih.gov/pubmed/32529715
http://dx.doi.org/10.1002/anie.202006212