Quantitative analysis of 11‐dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography/triple quadrupole mass spectrometry

RATIONALE: The activity of the glucocorticoid activating enzyme 11β‐hydroxysteroid dehydrogenase type‐1 (11βHSD1) is altered in diseases such as obesity, inflammation and psychiatric disorders. In rodents 11βHSD1 converts inert 11‐dehydrocorticosterone (11‐DHC) into the active form, corticosterone (...

Descripción completa

Detalles Bibliográficos
Autores principales: Verma, Manu, Sooy, Karen, Just, George, Nixon, Mark, Morgan, Ruth, Andrew, Ruth, Chapman, Karen E., Homer, Natalie Z.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Dai Games
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540072/
https://www.ncbi.nlm.nih.gov/pubmed/31677354
http://dx.doi.org/10.1002/rcm.8610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540072/
https://www.ncbi.nlm.nih.gov/pubmed/31677354
http://dx.doi.org/10.1002/rcm.8610

Ejemplares similares