Quantitative analysis of 11‐dehydrocorticosterone and corticosterone for preclinical studies by liquid chromatography/triple quadrupole mass spectrometry

RATIONALE: The activity of the glucocorticoid activating enzyme 11β‐hydroxysteroid dehydrogenase type‐1 (11βHSD1) is altered in diseases such as obesity, inflammation and psychiatric disorders. In rodents 11βHSD1 converts inert 11‐dehydrocorticosterone (11‐DHC) into the active form, corticosterone (...

Fuld beskrivelse

Bibliografiske detaljer
Autores principales: Verma, Manu, Sooy, Karen, Just, George, Nixon, Mark, Morgan, Ruth, Andrew, Ruth, Chapman, Karen E., Homer, Natalie Z.M.
Format: Online Artículo Texto
Sprog:English
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Dai Games
Online adgang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540072/
https://www.ncbi.nlm.nih.gov/pubmed/31677354
http://dx.doi.org/10.1002/rcm.8610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540072/
https://www.ncbi.nlm.nih.gov/pubmed/31677354
http://dx.doi.org/10.1002/rcm.8610

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