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TIR/BB-loop mimetic AS-1 protects vascular endothelial cells from injury induced by hypoxia/reoxygenation

Morphological and functional abnormalities of vascular endothelial cells (VECs) are risk factors of ischemia-reperfusion in skin flaps. Signaling pathway mediated by interleukin-1 receptor (IL-1R) is essential to hypoxia/reoxygenation (H/R) injury of VECs. While the TIR/BB-loop mimetic (AS-1) disrup...

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Detalles Bibliográficos
Autores principales: Zhang, Zhijia, Hou, Yuxing, Li, Jiantao, Tang, Chao, Que, Linli, Tan, Qian, Li, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540235/
https://www.ncbi.nlm.nih.gov/pubmed/32594023
http://dx.doi.org/10.7555/JBR.33.20190030