The Effects of Weak and Strong CYP3A Induction by Rifampicin on the Pharmacokinetics of Five Progestins and Ethinylestradiol Compared to Midazolam

It is known that co‐administration of CYP3A inducers may decrease the effectiveness of oral contraceptives containing progestins as mono‐preparations or combined with ethinylestradiol. In a randomized clinical drug‐drug interaction study, we investigated the effects of CYP3A induction on the pharmac...

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Detalles Bibliográficos
Autores principales: Wiesinger, Herbert, Klein, Stefan, Rottmann, Antje, Nowotny, Bettina, Riecke, Kai, Gashaw, Isabella, Brudny‐Klöppel, Margarete, Fricke, Robert, Höchel, Joachim, Friedrich, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540325/
https://www.ncbi.nlm.nih.gov/pubmed/32275771
http://dx.doi.org/10.1002/cpt.1848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540325/
https://www.ncbi.nlm.nih.gov/pubmed/32275771
http://dx.doi.org/10.1002/cpt.1848

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