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Minimal deuterium isotope effects in quantitation of dimethyl‐labeled complex proteomes analyzed with capillary zone electrophoresis/mass spectrometry
Stable heavy‐isotope labeling is commonly used in quantitative proteomics. Several common techniques incorporate deuterium ((2)H) as the heavy isotopic label using reductive amination with formaldehyde. Compared with alternatives, dimethyl labeling reagents are inexpensive and the labeling chemistry...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540333/ https://www.ncbi.nlm.nih.gov/pubmed/32548848 http://dx.doi.org/10.1002/elps.202000051 |