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Frequency and prognostic impact of PAX5 p.P80R in pediatric acute lymphoblastic leukemia patients treated on an AIEOP‐BFM acute lymphoblastic leukemia protocol

PAX5 is a member of the paired box (PAX) family of transcription factors involved in B‐cell development. PAX5 (P80R) has recently been described as a distinct genetic B‐cell precursor (BCP) acute lymphoblastic leukemia (ALL) subtype with a favorable prognosis in adults. In contrast, an unfavorable o...

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Detalles Bibliográficos
Autores principales: Jung, Mareike, Schieck, Maximilian, Hofmann, Winfried, Tauscher, Marcel, Lentes, Jana, Bergmann, Anke, Stelter, Marie, Möricke, Anja, Alten, Julia, Schlegelberger, Brigitte, Schrappe, Martin, Zimmermann, Martin, Stanulla, Martin, Cario, Gunnar, Steinemann, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540392/
https://www.ncbi.nlm.nih.gov/pubmed/32592278
http://dx.doi.org/10.1002/gcc.22882