The Sphingosine and Acyl Chains of Ceramide [NS] Show Very Different Structure and Dynamics That Challenge Our Understanding of the Skin Barrier

The lipid phase of the uppermost human skin layer is thought to comprise highly rigid lipids in an orthorhombic phase state to protect the body against the environment. By synthesizing sphingosine‐d(28) deuterated N‐lignoceroyl‐d‐erythro‐sphingosine (ceramide [NS]), we compare the structure and dyna...

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Detalles Bibliográficos
Autores principales: Engberg, Oskar, Kováčik, Andrej, Pullmannová, Petra, Juhaščik, Martin, Opálka, Lukáš, Huster, Daniel, Vávrová, Kateřina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540555/
https://www.ncbi.nlm.nih.gov/pubmed/32515145
http://dx.doi.org/10.1002/anie.202003375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540555/
https://www.ncbi.nlm.nih.gov/pubmed/32515145
http://dx.doi.org/10.1002/anie.202003375

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