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The Sphingosine and Acyl Chains of Ceramide [NS] Show Very Different Structure and Dynamics That Challenge Our Understanding of the Skin Barrier
The lipid phase of the uppermost human skin layer is thought to comprise highly rigid lipids in an orthorhombic phase state to protect the body against the environment. By synthesizing sphingosine‐d(28) deuterated N‐lignoceroyl‐d‐erythro‐sphingosine (ceramide [NS]), we compare the structure and dyna...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540555/ https://www.ncbi.nlm.nih.gov/pubmed/32515145 http://dx.doi.org/10.1002/anie.202003375 |