Fluorine‐Induced Pseudo‐Anomeric Effects in Methoxycyclohexanes through Electrostatic 1,3‐Diaxial Interactions

We report counter‐intuitive axial preferences in non‐stereochemically biased, selectively fluorinated methoxycyclohexanes. These pseudo‐anomeric effects are apparent when electronegative CF(2) groups are placed at the C‐2, C‐4 and C‐6 positions of the cyclohexane ring to render the C‐3/5 axial hydro...

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Detalles Bibliográficos
Autores principales: Piscelli, Bruno A., Sanders, William, Yu, Cihang, Al Maharik, Nawaf, Lebl, Thomas, Cormanich, Rodrigo A., O'Hagan, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540582/
https://www.ncbi.nlm.nih.gov/pubmed/32588927
http://dx.doi.org/10.1002/chem.202003058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540582/
https://www.ncbi.nlm.nih.gov/pubmed/32588927
http://dx.doi.org/10.1002/chem.202003058

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