Cargando…

Bacterial metabolism of bile acids promotes peripheral Treg cell generation

Intestinal health relies on the immunosuppressive activity of CD4(+) regulatory T (Treg) cells(1). Foxp3 expression defines this lineage and can be induced extrathymically by dietary or commensal-derived antigens in a process assisted by the Foxp3 enhancer CNS1 (conserved non-coding sequence 1)(2–4)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Campbell, Clarissa, McKenney, Peter T., Konstantinovsky, Daniel, Isaeva, Olga I., Schizas, Michael, Verter, Jacob, Mai, Cheryl, Jin, Wen-Bing, Guo, Chun-Jun, Violante, Sara, Ramos, Ruben J., Cross, Justin R., Kadaveru, Krishna, Hambor, John, Rudensky, Alexander Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540721/ https://www.ncbi.nlm.nih.gov/pubmed/32461639 http://dx.doi.org/10.1038/s41586-020-2193-0

Ejemplares similares

Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation
por: Arpaia, Nicholas, et al.
Publicado: (2013)

Regulatory T Cells Function in Established Systemic Inflammation and Reverse Fatal Autoimmunity
por: Hu, Wei, et al.
Publicado: (2021)

CXCR4(+) Treg cells control serum IgM levels and natural IgM autoantibody production by B-1 cells in the bone marrow
por: Elias, Shlomo, et al.
Publicado: (2022)

Bile acid metabolites control Th17 and Treg cell differentiation
por: Hang, Saiyu, et al.
Publicado: (2019)

T reg cell–intrinsic requirements for ST2 signaling in health and neuroinflammation
por: Hemmers, Saskia, et al.
Publicado: (2020)

Precision microbiome restoration of bile acid-mediated resistance to Clostridium difficile
por: Buffie, Charlie G., et al.
Publicado: (2014)

Pathological conditions re-shape physiological Tregs into pathological Tregs
por: Yang, William Y, et al.
Publicado: (2015)

Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity
por: Yadav, Mahesh, et al.
Publicado: (2013)

Tissue resident memory T cells create genetically distinct immune microenvironments within melanoma metastasis
por: Dhodapkar, Kavita, et al.
Publicado: (2015)

IFNγ+ Treg in-vivo and in-vitro represent both activated nTreg and peripherally induced aTreg and remain phenotypically stable in-vitro after removal of the stimulus
por: Daniel, Volker, et al.
Publicado: (2015)

FXR mediates T cell-intrinsic responses to reduced feeding during infection
por: Campbell, Clarissa, et al.
Publicado: (2020)

A nonimmune function of T cells in promoting lung tumor progression
por: Green, Jesse A., et al.
Publicado: (2017)

Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS
por: Beers, David R., et al.
Publicado: (2022)

Nuclear receptor LXRβ controls fitness and functionality of activated T cells
por: Michaels, Anthony J., et al.
Publicado: (2020)

Challenges associated with blood banks and blood donations during the COVID-19 pandemic
por: Sen-Crowe, Brendon, et al.
Publicado: (2021)

CD49b defines functionally mature Treg cells that survey skin and vascular tissues
por: Fan, Xiying, et al.
Publicado: (2018)

Conducting Educational Design Research
por: McKenney, Susan
Publicado: (2013)

Synergistic autoinhibition and activation mechanisms control kinesin-1 motor activity
por: Chiba, Kyoko, et al.
Publicado: (2022)

Synergistic autoinhibition and activation mechanisms control kinesin-1 motor activity
por: Chiba, Kyoko, et al.
Publicado: (2022)

A novel approach to T-cell receptor beta chain (TCRB) repertoire encoding using lossless string compression
por: Konstantinovsky, Thomas, et al.
Publicado: (2023)

Dendritic Cells Regulate Treg-Th17 Axis in Obstructive Phase of Bile Duct Injury in Murine Biliary Atresia
por: Liu, Yong-jun, et al.
Publicado: (2015)

Descubriendo Comillas : una joya en la Corona Española /
por: McKenney, Kenneth, 1929-
Publicado: (1995)

Supreme Court Decision: No. 67. October Term, 1880
por: McKenney, James H.
Publicado: (1881)

Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance
por: ZHAO, JIANBIN, et al.
Publicado: (2016)

Alemtuzumab in Multiple Sclerosis: Short- and Long-Term Effects of Immunodepletion on the Peripheral Treg Compartment
por: Haas, Jürgen, et al.
Publicado: (2019)

Imbalance of Th17 and Treg in peripheral blood mononuclear cells of active tuberculosis patients
por: Luo, Jie, et al.
Publicado: (2016)

Peripheral Th17/Treg cell-mediated immunity imbalance in allergic rhinitis patients,
por: Huang, Xuekun, et al.
Publicado: (2014)

3rd Annual October Astrophysics Conference in Maryland
por: Holt, S S, et al.
Publicado: (1992)

Map framework: a formal model of maps as a fundamental data type in information systems
por: McKenney, Mark, et al.
Publicado: (2016)

Towards distribution-based control of social networks
por: McKenney, Dave, et al.
Publicado: (2018)

Type 1 primary hyperoxaluria in a male infant
por: Waddell, Benjamin, et al.
Publicado: (2017)

Inflammation Determines the Capacity of Allogenic Endothelial Cells to Regulate Human Treg Expansion
por: Cross, Amy Rachael, et al.
Publicado: (2021)

Treg/IL-17 Ratio and Treg Differentiation in Patients with COPD
por: Jin, Yang, et al.
Publicado: (2014)

ICOS(+) Tregs: A Functional Subset of Tregs in Immune Diseases
por: Li, Dan-Yang, et al.
Publicado: (2020)

Myocardial-Treg Crosstalk: How to Tame a Wolf
por: Weiß, Emil, et al.
Publicado: (2022)

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127(pos) Depletion, Treg Expansion, and Treg Cryopreservation
por: Peters, Jorieke H., et al.
Publicado: (2008)

In-depth immunophenotyping data of IL-6R on the human peripheral regulatory T cell (Treg) compartment
por: Ferreira, Ricardo C., et al.
Publicado: (2017)

Imbalanced Th17/Treg in peripheral blood of adult patients with immunoglobulin A vasculitis nephritis
por: Xue, Xue, et al.
Publicado: (2021)

Educational design research: Portraying, conducting, and enhancing productive scholarship
por: McKenney, Susan, et al.
Publicado: (2020)

Control of motor landing and processivity by the CAP-Gly domain in the KIF13B tail
por: Fan, Xiangyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1r165okr61nbpcg5156fmc7nkv