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Synthesis and in vitro anticancer activities of substituted N-(4′-nitrophenyl)-l-prolinamides

Prolinamides are present in secondary metabolites and have wide-ranging biological properties as well as antimicrobial and cytotoxic activities. N-(4′-substituted phenyl)-l-prolinamides 4a–4w were synthesized in two steps, starting from the condensation of p-fluoronitrobenzene 1a–1b with l-proline 2...

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Detalles Bibliográficos
Autores principales: Osinubi, Adejoke, Izunobi, Josephat, Bao, Xiaoguang, Asekun, Olayinka, Kong, Jiehong, Gui, Chunshan, Familoni, Oluwole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540745/
https://www.ncbi.nlm.nih.gov/pubmed/33047051
http://dx.doi.org/10.1098/rsos.200906