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Exploration of small-molecule entry disruptors for chikungunya virus by targeting matrix remodelling associated protein

BACKGROUND AND PURPOSE: A genome-wide clustered regularly interspaced short palindromic repeats- associated protein 9-based screen has revealed that the cell adhesion molecule matrix remodelling associated protein 8 (Mxra8) acts as an entry mediator for many alphaviruses including chikungunya virus....

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Detalles Bibliográficos
Autores principales: Kumar, Avinash, Rathi, Ekta, Kini, Suvarna Ganesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540810/
https://www.ncbi.nlm.nih.gov/pubmed/33088330
http://dx.doi.org/10.4103/1735-5362.288437