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Analysis of mutational and proteomic heterogeneity of gastric cancer suggests an effective pipeline to monitor post-treatment tumor burden using circulating tumor DNA

Circulating tumor DNA (ctDNA) is released from tumor cells into blood in advanced cancer patients. Although gene mutations in individual tumors can be diverse and heterogenous, ctDNA has the potential to provide comprehensive biomarker information. Here, we performed multi-region sampling (three sit...

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Detalles Bibliográficos
Autores principales: Sasaki, Noriyuki, Iwaya, Takeshi, Chiba, Takehiro, Fujita, Masashi, Ju, Zhenlin, Endo, Fumitaka, Yaegashi, Mizunori, Hachiya, Tsuyoshi, Sugimoto, Ryo, Sugai, Tamotsu, Siwak, Doris R., Liotta, Lance A., Lu, Yiling, Mills, Gordon B., Nakagawa, Hidewaki, Nishizuka, Satoshi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540850/
https://www.ncbi.nlm.nih.gov/pubmed/33027286
http://dx.doi.org/10.1371/journal.pone.0239966