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Analysis of mutational and proteomic heterogeneity of gastric cancer suggests an effective pipeline to monitor post-treatment tumor burden using circulating tumor DNA
Circulating tumor DNA (ctDNA) is released from tumor cells into blood in advanced cancer patients. Although gene mutations in individual tumors can be diverse and heterogenous, ctDNA has the potential to provide comprehensive biomarker information. Here, we performed multi-region sampling (three sit...
Autores principales: | Sasaki, Noriyuki, Iwaya, Takeshi, Chiba, Takehiro, Fujita, Masashi, Ju, Zhenlin, Endo, Fumitaka, Yaegashi, Mizunori, Hachiya, Tsuyoshi, Sugimoto, Ryo, Sugai, Tamotsu, Siwak, Doris R., Liotta, Lance A., Lu, Yiling, Mills, Gordon B., Nakagawa, Hidewaki, Nishizuka, Satoshi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540850/ https://www.ncbi.nlm.nih.gov/pubmed/33027286 http://dx.doi.org/10.1371/journal.pone.0239966 |
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