The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies

We have created the immunodeficient SRG rat, a Sprague-Dawley Rag2/Il2rg double knockout that lacks mature B cells, T cells, and circulating NK cells. This model has been tested and validated for use in oncology (SRG OncoRat(®)). The SRG rat demonstrates efficient tumor take rates and growth kinetic...

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Detalles Bibliográficos
Autores principales: Noto, Fallon K., Sangodkar, Jaya, Adedeji, Bisoye Towobola, Moody, Sam, McClain, Christopher B., Tong, Ming, Ostertag, Eric, Crawford, Jack, Gao, Xiaohua, Hurst, Lauren, O’Connor, Caitlin M., Hanson, Erika N., Izadmehr, Sudeh, Tohmé, Rita, Narla, Jyothsna, LeSueur, Kristin, Bhattacharya, Kajari, Rupani, Amit, Tayeh, Marwan K., Innis, Jeffrey W., Galsky, Matthew D., Evers, B. Mark, DiFeo, Analisa, Narla, Goutham, Jamling, Tseten Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540894/
https://www.ncbi.nlm.nih.gov/pubmed/33027304
http://dx.doi.org/10.1371/journal.pone.0240169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540894/
https://www.ncbi.nlm.nih.gov/pubmed/33027304
http://dx.doi.org/10.1371/journal.pone.0240169

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