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DRP1 promotes lactate utilization in KRAS‐mutant non‐small‐cell lung cancer cells

Metabolic alterations are well documented in various cancers. Non‐small‐cell lung cancers (NSCLCs) preferentially use lactate as the primary carbon source, but the underlying mechanisms are not well understood. We developed a lactate‐dependent cell proliferation assay and found that dynamin‐related...

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Detalles Bibliográficos
Autores principales: Hu, Mangze, Zhao, Yu, Cao, Yuejiao, Tang, Qianru, Feng, Ziqin, Ni, Jun, Zhou, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540982/
https://www.ncbi.nlm.nih.gov/pubmed/32767829
http://dx.doi.org/10.1111/cas.14603