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Neuroblastoma patient‐derived cultures are enriched for a mesenchymal gene signature and reflect individual drug response

Ex vivo evaluation of personalized models can facilitate individualized treatment selection for patients, and advance the discovery of novel therapeutic options. However, for embryonal malignancies, representative primary cultures have been difficult to establish. We developed patient‐derived cell c...

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Detalles Bibliográficos
Autores principales: Hee, Esther, Wong, Meng Kang, Tan, Sheng Hui, Choo, Zhang’E, Kuick, Chik Hong, Ling, Sharon, Yong, Min Hwee, Jain, Sudhanshi, Lian, Derrick W. Q., Ng, Eileen H. Q., Yong, Yvonne F. L., Ren, Mee Hiong, Syed Sulaiman, Nurfarhanah, Low, Sharon Y. Y., Chua, Yong Wei, Syed, Muhammad Fahmy, Lim, Tony K. H., Soh, Shui Yen, Iyer, Prasad, Seng, Michaela S. F., Lam, Joyce C. M., Tan, Enrica E. K., Chan, Mei Yoke, Tan, Ah Moy, Chen, Yong, Chen, Zhixiong, Chang, Kenneth T. E., Loh, Amos Hong Pheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7540996/
https://www.ncbi.nlm.nih.gov/pubmed/32777141
http://dx.doi.org/10.1111/cas.14610