Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke

Failure of neurons to efficiently repair DNA double-strand breaks (DSBs) contributes to cerebral damage after stroke. However, the molecular machinery that regulates DNA repair in this neurological disorder is unknown. Here, we found that DSBs in oxygen/glucose-deprived (OGD) neurons spatiotemporall...

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Detalles Bibliográficos
Autores principales: Sánchez-Morán, Irene, Rodríguez, Cristina, Lapresa, Rebeca, Agulla, Jesús, Sobrino, Tomás, Castillo, José, Bolaños, Juan P., Almeida, Angeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541066/
https://www.ncbi.nlm.nih.gov/pubmed/33028529
http://dx.doi.org/10.1126/sciadv.abc5702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541066/
https://www.ncbi.nlm.nih.gov/pubmed/33028529
http://dx.doi.org/10.1126/sciadv.abc5702

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