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Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke
Failure of neurons to efficiently repair DNA double-strand breaks (DSBs) contributes to cerebral damage after stroke. However, the molecular machinery that regulates DNA repair in this neurological disorder is unknown. Here, we found that DSBs in oxygen/glucose-deprived (OGD) neurons spatiotemporall...
Autores principales: | Sánchez-Morán, Irene, Rodríguez, Cristina, Lapresa, Rebeca, Agulla, Jesús, Sobrino, Tomás, Castillo, José, Bolaños, Juan P., Almeida, Angeles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541066/ https://www.ncbi.nlm.nih.gov/pubmed/33028529 http://dx.doi.org/10.1126/sciadv.abc5702 |
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