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Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications

The widespread occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein of SARS-CoV-2 binds with angiotensin-converting enzyme 2 (ACE2) as a functional “receptor” and then enters into host cells to re...

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Detalles Bibliográficos
Autores principales: Iwasaki, Masae, Saito, Junichi, Zhao, Hailin, Sakamoto, Atsuhiro, Hirota, Kazuyoshi, Ma, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541099/
https://www.ncbi.nlm.nih.gov/pubmed/33029758
http://dx.doi.org/10.1007/s10753-020-01337-3