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Tetrandrine sensitizes nasopharyngeal carcinoma cells to irradiation by inducing autophagy and inhibiting MEK/ERK pathway

Radioresistance was the main reason for local recurrence and metastasis of nasopharyngeal carcinoma. Tetrandrine is reported as an antitumor drug via inducing cell cycle arrest and apoptosis. In this study, the radiosensitization effects of maximum noncytotoxic doses of tetrandrine in nasopharyngeal...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Yao, Zhouzhou, Lai, Xiaoping, Bao, Hongwei, Li, Yue, Li, Shuaixiang, Chang, Lihong, Zhang, Gehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541130/
https://www.ncbi.nlm.nih.gov/pubmed/32780562
http://dx.doi.org/10.1002/cam4.3356