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Immunosuppressive role of CD11b(+)CD33(+)HLA‐DR(−) myeloid‐derived suppressor cells‐like blast subpopulation in acute myeloid leukemia

OBJECTIVE: Myeloid‐derived suppressor cells (MDSCs) facilitate tumor growth and development by suppressing T cell function; however, their role in acute myeloid leukemia (AML) remains unclear. Here, we investigated the immunosuppressive role and prognostic value of blasts with an MDSC‐like phenotype...

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Detalles Bibliográficos
Autores principales: Hyun, Shin Young, Na, Eun Jung, Jang, Ji Eun, Chung, Haerim, Kim, Soo Jeong, Kim, Jin Seok, Kong, Jee Hyun, Shim, Kwang Yong, Lee, Jong In, Min, Yoo Hong, Cheong, June‐Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541151/
https://www.ncbi.nlm.nih.gov/pubmed/32780544
http://dx.doi.org/10.1002/cam4.3360