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The Potential Role of Coagulation Factor Xa in the Pathophysiology of COVID-19: A Role for Anticoagulants as Multimodal Therapeutic Agents

SARS-CoV-2 infection (COVID-19) results in local and systemic activation of inflammation and coagulation. In this review article, we will discuss the potential role of coagulation factor Xa (FXa) in the pathophysiology of COVID-19. FXa, a serine protease, has been shown to play a role in the cleavag...

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Detalles Bibliográficos
Autores principales: Frydman, Galit H., Streiff, Michael B., Connors, Jean M., Piazza, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541169/
https://www.ncbi.nlm.nih.gov/pubmed/33043235
http://dx.doi.org/10.1055/s-0040-1718415