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Novel single-domain antibodies against the EGFR domain III epitope exhibit the anti-tumor effect
BACKGROUND: Monoclonal antibodies (mAbs) have been used for cancer therapy. They are large and have some disadvantages limiting their use. Smaller antibody fragments are needed as their alternatives. A fully human single-domain antibody (sdAb) has a small size of only 15 kDa and consists of only the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541222/ https://www.ncbi.nlm.nih.gov/pubmed/33023595 http://dx.doi.org/10.1186/s12967-020-02538-y |