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Novel single-domain antibodies against the EGFR domain III epitope exhibit the anti-tumor effect

BACKGROUND: Monoclonal antibodies (mAbs) have been used for cancer therapy. They are large and have some disadvantages limiting their use. Smaller antibody fragments are needed as their alternatives. A fully human single-domain antibody (sdAb) has a small size of only 15 kDa and consists of only the...

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Detalles Bibliográficos
Autores principales:	Chen, Tao, Liu, Xue, Hong, Haifeng, Wei, Henry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541222/ https://www.ncbi.nlm.nih.gov/pubmed/33023595 http://dx.doi.org/10.1186/s12967-020-02538-y

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