NF-κB and pSTAT3 synergistically drive G6PD overexpression and facilitate sensitivity to G6PD inhibition in ccRCC

BACKGROUND: Glucose 6-phosphate dehydrogenase (G6PD) serves key roles in cancer cell metabolic reprogramming, and has been reported to be involved in certain carcinogenesis. Previous results from our laboratory demonstrated that overexpressed G6PD was a potential prognostic biomarker in clear cell r...

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Detalles Bibliográficos
Autores principales: Zhang, Qiao, Yang, Zhe, Ni, Yueli, Bai, Honggang, Han, Qiaoqiao, Yi, Zihan, Yi, Xiaojia, Agbana, Yannick Luther, Kuang, Yingmin, Zhu, Yuechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541270/
https://www.ncbi.nlm.nih.gov/pubmed/33041664
http://dx.doi.org/10.1186/s12935-020-01576-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541270/
https://www.ncbi.nlm.nih.gov/pubmed/33041664
http://dx.doi.org/10.1186/s12935-020-01576-2

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