Impact of ambient temperature on inflammation-induced encephalopathy in endotoxemic mice—role of phosphoinositide 3-kinase gamma

BACKGROUND: Sepsis-associated encephalopathy (SAE) is an early and frequent event of infection-induced systemic inflammatory response syndrome. Phosphoinositide 3-kinase γ (PI3Kγ) is linked to neuroinflammation and inflammation-related microglial activity. In homeotherms, variations in ambient tempe...

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Detalles Bibliográficos
Autores principales: Lang, Guang-Ping, Ndongson-Dongmo, Bernadin, Lajqi, Trim, Brodhun, Michael, Han, Yingying, Wetzker, Reinhard, Frasch, Martin G., Bauer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541275/
https://www.ncbi.nlm.nih.gov/pubmed/33028343
http://dx.doi.org/10.1186/s12974-020-01954-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541275/
https://www.ncbi.nlm.nih.gov/pubmed/33028343
http://dx.doi.org/10.1186/s12974-020-01954-7

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