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Impact of ambient temperature on inflammation-induced encephalopathy in endotoxemic mice—role of phosphoinositide 3-kinase gamma

BACKGROUND: Sepsis-associated encephalopathy (SAE) is an early and frequent event of infection-induced systemic inflammatory response syndrome. Phosphoinositide 3-kinase γ (PI3Kγ) is linked to neuroinflammation and inflammation-related microglial activity. In homeotherms, variations in ambient tempe...

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Detalles Bibliográficos
Autores principales:	Lang, Guang-Ping, Ndongson-Dongmo, Bernadin, Lajqi, Trim, Brodhun, Michael, Han, Yingying, Wetzker, Reinhard, Frasch, Martin G., Bauer, Reinhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541275/ https://www.ncbi.nlm.nih.gov/pubmed/33028343 http://dx.doi.org/10.1186/s12974-020-01954-7

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