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Axonal Protection by Nicotinamide Riboside via SIRT1-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration

Nicotinamide adenine dinucleotide (NAD(+)) synthesis pathway has been involved in many biological functions. Nicotinamide riboside (NR) is widely used as an NAD(+) precursor and known to increase NAD(+) level in several tissues. The present study aimed to examine the effect of NR on tumor necrosis f...

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Detalles Bibliográficos
Autores principales: Kitaoka, Yasushi, Sase, Kana, Tsukahara, Chihiro, Fujita, Naoki, Arizono, Ibuki, Takagi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541376/
https://www.ncbi.nlm.nih.gov/pubmed/32820458
http://dx.doi.org/10.1007/s12035-020-02063-5