The Epilepsy-Related Protein PCDH19 Regulates Tonic Inhibition, GABA(A)R Kinetics, and the Intrinsic Excitability of Hippocampal Neurons

PCDH19 encodes for protocadherin-19 (PCDH19), a cell-adhesion molecule of the cadherin superfamily preferentially expressed in the brain. PCDH19 mutations cause a neurodevelopmental syndrome named epileptic encephalopathy, early infantile, 9 (EIEE9) characterized by seizures associated with cognitiv...

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Detalles Bibliográficos
Autores principales: Serratto, Giulia M., Pizzi, Erika, Murru, Luca, Mazzoleni, Sara, Pelucchi, Silvia, Marcello, Elena, Mazzanti, Michele, Passafaro, Maria, Bassani, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541378/
https://www.ncbi.nlm.nih.gov/pubmed/32880860
http://dx.doi.org/10.1007/s12035-020-02099-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541378/
https://www.ncbi.nlm.nih.gov/pubmed/32880860
http://dx.doi.org/10.1007/s12035-020-02099-7

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