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The Epilepsy-Related Protein PCDH19 Regulates Tonic Inhibition, GABA(A)R Kinetics, and the Intrinsic Excitability of Hippocampal Neurons
PCDH19 encodes for protocadherin-19 (PCDH19), a cell-adhesion molecule of the cadherin superfamily preferentially expressed in the brain. PCDH19 mutations cause a neurodevelopmental syndrome named epileptic encephalopathy, early infantile, 9 (EIEE9) characterized by seizures associated with cognitiv...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541378/ https://www.ncbi.nlm.nih.gov/pubmed/32880860 http://dx.doi.org/10.1007/s12035-020-02099-7 |