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PKCγ-Mediated Phosphorylation of CRMP2 Regulates Dendritic Outgrowth in Cerebellar Purkinje Cells

The signalling protein PKCγ is a major regulator of Purkinje cell development and synaptic function. We have shown previously that increased PKCγ activity impairs dendritic development of cerebellar Purkinje cells. Mutations in the protein kinase Cγ gene (PRKCG) cause spinocerebellar ataxia type 14...

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Detalles Bibliográficos
Autores principales: Winkler, Sabine C., Shimobayashi, Etsuko, Kapfhammer, Josef P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541385/
https://www.ncbi.nlm.nih.gov/pubmed/32860158
http://dx.doi.org/10.1007/s12035-020-02038-6