Analyzing the M. tuberculosis immune response by T cell receptor clustering with GLIPH2 and genome-wide antigen screening

CD4(+) T cells are critical to fighting pathogens, but a comprehensive analysis of human T cell specificities is hindered by the diversity of HLA alleles (>20,000) and the complexity of many pathogen genomes. We previously described GLIPH, an algorithm to cluster T cell receptors (TCRs) that reco...

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Detalles Bibliográficos
Autores principales: Huang, Huang, Wang, Chunlin, Rubelt, Florian, Scriba, Thomas J., Davis, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541396/
https://www.ncbi.nlm.nih.gov/pubmed/32341563
http://dx.doi.org/10.1038/s41587-020-0505-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541396/
https://www.ncbi.nlm.nih.gov/pubmed/32341563
http://dx.doi.org/10.1038/s41587-020-0505-4

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