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Tracing the cellular basis of islet specification in mouse pancreas

Pancreatic islets play an essential role in regulating blood glucose level. Although the molecular pathways underlying islet cell differentiation are beginning to be resolved, the cellular basis of islet morphogenesis and fate allocation remain unclear. By combining unbiased and targeted lineage tra...

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Detalles Bibliográficos
Autores principales: Sznurkowska, Magdalena K., Hannezo, Edouard, Azzarelli, Roberta, Chatzeli, Lemonia, Ikeda, Tatsuro, Yoshida, Shosei, Philpott, Anna, Simons, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541446/
https://www.ncbi.nlm.nih.gov/pubmed/33028844
http://dx.doi.org/10.1038/s41467-020-18837-3