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Analysis of Plasmodium vivax schizont transcriptomes from field isolates reveals heterogeneity of expression of genes involved in host-parasite interactions

Plasmodium vivax gene regulation remains difficult to study due to the lack of a robust in vitro culture method, low parasite densities in peripheral circulation and asynchronous parasite development. We adapted an RNA-seq protocol “DAFT-seq” to sequence the transcriptome of four P. vivax field isol...

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Detalles Bibliográficos
Autores principales: Siegel, Sasha V., Chappell, Lia, Hostetler, Jessica B., Amaratunga, Chanaki, Suon, Seila, Böhme, Ulrike, Berriman, Matthew, Fairhurst, Rick M., Rayner, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541449/
https://www.ncbi.nlm.nih.gov/pubmed/33028892
http://dx.doi.org/10.1038/s41598-020-73562-7