ATP modulates SLC7A5 (LAT1) synergistically with cholesterol

The plasma membrane transporter hLAT1 is responsible for providing cells with essential amino acids. hLAT1 is over-expressed in virtually all human cancers making the protein a hot-spot in the fields of cancer and pharmacology research. However, regulatory aspects of hLAT1 biology are still poorly u...

Descripción completa

Detalles Bibliográficos
Autores principales: Cosco, Jessica, Scalise, Mariafrancesca, Colas, Claire, Galluccio, Michele, Martini, Riccardo, Rovella, Filomena, Mazza, Tiziano, Ecker, Gerhard F., Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541457/
https://www.ncbi.nlm.nih.gov/pubmed/33028978
http://dx.doi.org/10.1038/s41598-020-73757-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541457/
https://www.ncbi.nlm.nih.gov/pubmed/33028978
http://dx.doi.org/10.1038/s41598-020-73757-y

Ejemplares similares