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Inhibition of eNOS by L-NAME resulting in rat hind limb developmental defects through PFKFB3 mediated angiogenetic pathway

l-arginine/NOS/NO signaling pathway plays a critical role in controlling variety of vascular diseases. However, whether NOS inhibition by L-NAME suppresses late embryonic development is undefined. The aim of this study is to determine whether NOS inhibition by L-NAME is critical for late embryonic r...

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Detalles Bibliográficos
Autores principales: Wu, Ziqiang, Yao, Huan, Xu, Huan, Wang, Yang, Hu, Wangming, Lou, Guanhua, Zhang, Lingling, Huang, Cong, Jiang, Cen, Zhou, Shiyi, Shi, Yaping, Chen, Xiongbing, Yang, Lan, Xu, Yiming, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541470/
https://www.ncbi.nlm.nih.gov/pubmed/33028909
http://dx.doi.org/10.1038/s41598-020-74011-1