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Sequence-to-function deep learning frameworks for engineered riboregulators

While synthetic biology has revolutionized our approaches to medicine, agriculture, and energy, the design of completely novel biological circuit components beyond naturally-derived templates remains challenging due to poorly understood design rules. Toehold switches, which are programmable nucleic...

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Detalles Bibliográficos
Autores principales: Valeri, Jacqueline A., Collins, Katherine M., Ramesh, Pradeep, Alcantar, Miguel A., Lepe, Bianca A., Lu, Timothy K., Camacho, Diogo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541510/
https://www.ncbi.nlm.nih.gov/pubmed/33028819
http://dx.doi.org/10.1038/s41467-020-18676-2