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Sequence-to-function deep learning frameworks for engineered riboregulators
While synthetic biology has revolutionized our approaches to medicine, agriculture, and energy, the design of completely novel biological circuit components beyond naturally-derived templates remains challenging due to poorly understood design rules. Toehold switches, which are programmable nucleic...
Autores principales: | Valeri, Jacqueline A., Collins, Katherine M., Ramesh, Pradeep, Alcantar, Miguel A., Lepe, Bianca A., Lu, Timothy K., Camacho, Diogo M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541510/ https://www.ncbi.nlm.nih.gov/pubmed/33028819 http://dx.doi.org/10.1038/s41467-020-18676-2 |
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