Proteasomal degradation of polycomb-group protein CBX6 confers MMP-2 expression essential for mesothelioma invasion

The aggressive invasiveness of malignant mesothelioma limits cancer therapy, however, the molecular mechanisms underlying the invasiveness remain largely unknown. Here we found that the matrix metalloproteinase-2 (MMP-2) was required for the invasion of mesothelioma cells in the collagen matrix and...

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Detalles Bibliográficos
Autores principales: Sakai, Katsuya, Nishiuchi, Takumi, Tange, Shoichiro, Suzuki, Yoshinori, Yano, Seiji, Terashima, Minoru, Suzuki, Takeshi, Matsumoto, Kunio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541533/
https://www.ncbi.nlm.nih.gov/pubmed/33028834
http://dx.doi.org/10.1038/s41598-020-72448-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541533/
https://www.ncbi.nlm.nih.gov/pubmed/33028834
http://dx.doi.org/10.1038/s41598-020-72448-y

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