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Alteration of genome folding via contact domain boundary insertion

Animal chromosomes are partitioned into contact domains. Pathogenic domain disruptions can result from chromosomal rearrangements or perturbation of architectural factors. However, such broad-scale alterations are insufficient to define the minimal requirements for domain formation. Moreover, to wha...

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Detalles Bibliográficos
Autores principales: Zhang, Di, Huang, Peng, Sharma, Malini, Keller, Cheryl A., Giardine, Belinda, Zhang, Haoyue, Gilgenast, Thomas G., Phillips-Cremins, Jennifer E., Hardison, Ross C., Blobel, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541666/
https://www.ncbi.nlm.nih.gov/pubmed/32868908
http://dx.doi.org/10.1038/s41588-020-0680-8