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Alteration of genome folding via contact domain boundary insertion
Animal chromosomes are partitioned into contact domains. Pathogenic domain disruptions can result from chromosomal rearrangements or perturbation of architectural factors. However, such broad-scale alterations are insufficient to define the minimal requirements for domain formation. Moreover, to wha...
Autores principales: | Zhang, Di, Huang, Peng, Sharma, Malini, Keller, Cheryl A., Giardine, Belinda, Zhang, Haoyue, Gilgenast, Thomas G., Phillips-Cremins, Jennifer E., Hardison, Ross C., Blobel, Gerd A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541666/ https://www.ncbi.nlm.nih.gov/pubmed/32868908 http://dx.doi.org/10.1038/s41588-020-0680-8 |
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