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Detecting chromatin interactions between and along sister chromatids with SisterC

Chromosome segregation requires both compaction and disentanglement of sister chromatids. We describe SisterC, a chromosome conformation capture assay that distinguishes interactions between and along identical sister chromatids. SisterC employs BrdU incorporation during S-phase to label newly repli...

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Detalles Bibliográficos
Autores principales: Oomen, Marlies E., Hedger, Adam K., Watts, Jonathan K., Dekker, Job
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541687/
https://www.ncbi.nlm.nih.gov/pubmed/32968250
http://dx.doi.org/10.1038/s41592-020-0930-9